Like all medicines, Sayana Press can cause side effects, please see the Patient Information Leaflet for more information
Please familiarise yourself with this section and re-read it regularly.
Talk to your doctor, pharmacist or nurse before using SAYANA PRESS.
Before your doctor prescribes SAYANA PRESS, you may need to have a physical examination. It is important to tell your doctor if you have, or have had in the past, any of the following conditions. Your doctor will then discuss with you whether SAYANA PRESS is suitable for you.
Tell your doctor if you have:
- Migraine headaches
- Diabetes or a family history of diabetes
- Severe pain or swelling in the calf (indicating a possible clot in the leg, which may be called phlebitis)
- A blood clot in the lung (pulmonary embolism)
- A blood clot in your eye affecting your vision (retinal thrombosis)
- A history of heart disease or cholesterol problems including any family history
- Past history of depression
- Irregular, light, or heavy menstrual periods
- An unusual breast x-ray, fibrocystic breast disease, breast nodules or lumps, or bleeding from your nipples
- A stroke
- Family history of breast cancer
- Kidney disease
- High blood pressure
- Asthma
- Epilepsy
- Psychiatric disorders - Some women using hormonal contraceptives including SAYANA PRESS have reported depression or depressed mood. Depression can be serious and may sometimes lead to suicidal thoughts. If you experience mood changes and depressive symptoms contact your doctor for further medical advice as soon as possible.
- Bone health, blood clots and possible risk of cancer - for information about effects on these areas, please see the ‘While on Sayana’ section and/or read the Patient Information Leaflet.
Like all medicines, SAYANA PRESS can cause side effects, although not everybody gets them. If any of the side effects gets serious, or if you notice any side effects not listed in the Patient Information Leaflet, please tell your doctor or pharmacist.
If you are injecting SAYANA PRESS yourself and not seeing your doctor as regularly, it is important you are aware of possible side effects, how to recognise them and when to get urgent medical help. Please familiarise yourself with this section of the Patient Information Leaflet and re-read it regularly. If you are worried about any unusual symptoms or changes in your health, talk to your doctor, nurse or healthcare provider. If you experience any of the following serious side effects, seek medical help immediately:
- A serious allergic reaction (it is not known how frequently this occurs) Symptoms include sudden wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat, skin rash, hives. Allergic reactions may happen soon after injection or can take time to develop in some people. If any of these symptoms appear at any time, even if you have used Sayana Press before, seek medical help immediately.
- A blood clot in the lungs (it is not known how frequently this occurs) Symptoms include
- an unusual sudden cough (which may bring up blood)
- severe pain in the chest which may increase with deep breathing
- sudden unexplained breathlessness or rapid breathing
- severe light headedness or dizziness
- rapid or irregular heartbeat
- severe pain in your abdomen
- A blood clot in the leg (it is not known how frequently this occurs) Symptoms include severe pain or swelling in either of your legs or feet that may be accompanied by tenderness, warmth or discoloured skin
- A blood clot in the eye (it is not known how frequently this occurs) Symptoms include loss of vision, pain and swelling of the eye especially if sudden
- A stroke (it is not known how frequently this occurs) Symptoms include
- weakness or numbness of the face, arm or leg, especially on one side of the body
- sudden confusion, trouble speaking or understanding
- sudden trouble seeing in one or both eyes
- sudden trouble walking, dizziness, loss of balance or coordination
- sudden, severe or prolonged headache with no known cause
- loss of consciousness or fainting with or without seizure.
Common: (may affect up to 1 in 10 people) |
Uncommon: (may affect up to 1 in 100 people) |
Rare (may affect up to 1 in 1,000 people) |
Not Known (frequency cannot be estimated from the available data) |
- Weight increase
- Abdominal pain (cramps)
- Nausea
- Acne
- Amenorrhea (very light or no period)
- Heavy, frequent and/or unexpected bleeding
- Irregular periods
- Period pains
- Breast pain / tenderness
- Depression
- Tiredness
- Headache
- Injection site reactions (including pain,tenderness, lump, persistent skin indentation/dimpling). You may feel some soreness or see redness around the injection site immediately after an injection. Mild reactions like this are common. If you get a reaction that worries you in any way, is particularly painful, or does not get better after a short time please talk to your doctor.
- Irritability
- Anxiety
- Difficulty sleeping
- Decreased sexual feeling
- Vaginal irritation or itching
- Mood changes
- Dizziness
- Back pain
- Pain in limbs
- Abnormal cervical smear
|
- Drug allergy
- Hirsutism (abnormal hairiness)
- Feeling bloated
- Fluid retention
- Vaginal discharge
- Vaginal dryness
- Pain during sexual intercourse
- Ovarian cyst
- Pelvic pain
- Premenstrual syndrome
- Change in breast size
- Milky discharge from breasts in women who are not breast-feeding
- Change in appetite
- Muscle cramps
- Joint pain
- Sleepiness
- Migraine
- Vertigo (a spinning sensation)
- Hot flushes
- Fever
- High blood pressure
- Rapid heart rate
- Varicose veins
- Rash
- Itching
- Hives
- Hair loss
- Skin irritation
- Bruising
- Facial discolouration
- Inflammation in the veins (felt as tenderness or redness in the affected area)
- Nervousness
- Loss of bone mineral density (a test used to diagnose osteoporosis or weak bones)
- Decreased glucose tolerance (excess sugar level in the blood)
- Emotional disturbance
- Inability to achieve a sexual climax
- Abnormal liver function test results (blood tests to measure liver injury)
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- Breast cancer
- Weakness
- Weight decrease
- Deformation of skin at the injection site
- Injection site discolouration
|
- Osteoporosis (weak bones) including osteoporotic fractures
- Seizures
- Abnormal liver function such as yellowing of the skin or eyes (jaundice)
- Skin stretch marks
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The Sayana Press Patient Information Leaflet is available at this link:
https://www.medicines.org.uk/emc/product/3148/pil
If you think you have experienced a side effect from your medicine, you should report it to the MHRA through the Yellow Card Scheme. You should also contact Pfizer medical information on 01304 616161